Cortisol Awakening Response (CAR)

The Cortisol Awakening Response (CAR) represents the momentum of rising cortisol levels that begins several hours prior to awakening and includes an additional transient increase. It reflects a person's ability to cope with anticipated challenges and their perceptions of control around chronic stress.

CAR is calculated by a direct percent increase: the difference between the 30-minute cortisol level and the waking cortisol level, divided by the waking cortisol level, then multiplied by 100. A value of approximately 50% is expected, indicating HPA axis resiliency.

Multiple Autoimmune Reactivity ScrEEN™

A test that measures predictive antibodies, some of which can appear up to ten years before the clinical onset of disease. It helps assess possible tissue damage to multiple organs and is recommended for patients with diagnosed autoimmune disorders or chronic increased intestinal permeability. The test checks for IgG and IgG + IgA combined antibodies against various antigens, including those related to the thyroid, adrenal cortex, heart, liver, pancreas, and brain.

Food Immune Reactivity Testing Comprehensive and Unprecedented

ARRAY 10 analyzes 180 real-world food antigens—cooked, raw, and modified—in one panel. It also includes Array 3X for 11 wheat proteins and peptides, and Array 4 for gliadin cross-reactive foods, helping to significantly reduce false negatives and identify over-consumed foods on a gluten-free diet.

Blood-Brain Barrier Permeability

The Cyrex Laboratories Array 20, or Blood-Brain Barrier Permeability™ test, assesses the integrity of your blood-brain barrier by measuring IgG, IgA, and IgM antibodies to blood-brain barrier proteins. It's used for early investigation and management of contact sports-related Traumatic Brain Injury (TBI) and to evaluate blood-brain barrier breaches caused by stress, trauma, or environmental triggers, even without apparent concussion. This test also helps assess the increased risk of neurodegenerative disorders such as Multiple Sclerosis, Alzheimer's, Parkinson's, Epilepsy, and Stroke. It is recommended for individuals involved in contact sports or activities with force/shock to the body/head, those with intestinal permeability and elevated LPS or Occludin/Zonulin antibodies, or anyone experiencing changes in cognitive function.

Comprehensive Thyroid Assessment

This Comprehensive Thyroid Assessment provides a thorough evaluation of thyroid function by examining central regulation (TSH, FT4), peripheral conversion (FT3, RT3), and autoimmune involvement (Anti-Thyroglobulin and Anti-Thyroid Peroxidase antibodies).

This assessment is necessary because thyroid dysfunction can occur even when the central hypothalamus-pituitary-thyroid axis appears to be functioning normally. Problems with peripheral conversion of hormones and/or immune system interference can still significantly impact thyroid hormone production and its action at the cellular level. Therefore, a comprehensive assessment is crucial to adequately diagnose and understand the full scope of thyroid health.

Endo+

A crucial tool for a comprehensive evaluation of an individual's hormonal and genetic health. It provides in-depth analysis of sex hormones, adrenal function, estrogen metabolism, and thyroid health, along with optional genomic insights into detoxification, methylation, and hormonal bone formation. This detailed report is invaluable for practitioners to understand a patient's unique biological profile, enabling the creation of personalized and effective clinical management strategies.

GI Effects Comprehensive Profile

A powerful stool test that provides a detailed look into your digestive health. By analyzing key biomarkers related to digestion, inflammation, gut microbiome balance, and potential infections, this test helps identify root causes of gastrointestinal symptoms. Understanding these insights can empower you and your healthcare provider to develop targeted therapeutic strategies, optimize gut function, and improve overall well-being.

MycoTOX Profile

A urine-based test that assesses levels of 11 different mycotoxins, which are toxic substances produced by molds. Mycotoxins are common in the environment and can interfere with cellular processes, potentially causing damage to the skin, lungs, and gut microbiome, as well as leading to mitochondrial damage and glutathione depletion. Exposure can occur through inhalation, ingestion, or skin contact from mold spores, contaminated food, and water-damaged buildings.

TOXDetect Profile

A laboratory test developed by Mosaic Diagnostics that provides a comprehensive breakdown of metabolite levels, grouped by chemical class (phthalates, volatile organic compounds, pesticides, and other metabolites). The report summarizes elevated results and details each metabolite, including parent compounds and associated health impacts. The test aims to enhance insight into environmental toxin exposure and is intended for educational purposes, recommending consultation with a healthcare provider for interpretation and treatment.

Methylation Panel

A comprehensive test that provides insights into your body's methylation processes. This panel assesses genetic polymorphisms and key methylation metabolites to give a detailed picture of your methylation and transsulfuration balance. Understanding these pathways can help identify potential imbalances related to homocysteine levels, methyl group donors, and other critical metabolites involved in various bodily functions.

NutrEval Plasma

A comprehensive nutritional evaluation that assesses over 125 biomarkers across five key areas: amino acids, organic acids, essential and metabolic fatty acids, oxidative stress, and nutrient and toxic elements. This test helps identify functional imbalances and individual nutritional needs for targeted support.

OMICm Age

The Next Generation in Biological Age Measurement. Developed by TruDiagnostic's Bioinformatics & Research Department, the OMICm Age algorithm precisely calculates your biological age by analyzing nearly one million methylation patterns on your DNA.Built on extensive data from thousands of samples, including a partnership with Harvard University and Partners Biobank, OMICm Age leverages "Multi Omics" – integrating genomics, epigenomics, transcriptomics, proteomics, metabolomics, and phenomics. This advanced approach allows us to deliver the most accurate predictor of biological aging to date, demonstrating superior ability in predicting health and aging outcomes compared to previous methylation age clocks.

CardioMetabolic Profile

A comprehensive assessment of cardiovascular health by analyzing various markers related to lipids, inflammation, apolipoproteins, and metabolic risk. It identifies key indicators such as high total cholesterol, low HDL cholesterol, high LDL cholesterol, elevated VLDL, non-HDL cholesterol, and oxidized LDL, which are all associated with increased cardiovascular disease risk. The report also highlights the significance of small dense LDL cholesterol as a highly atherogenic subtype and assesses inflammatory markers like PLAC and hsCRP, alongside homocysteine levels. Additionally, it examines ratios like Total Cholesterol: HDL-C, LDL-C: HDL-C, and Apo B: Apo A-1, providing deeper insights into lipid metabolism and cardiovascular risk. The profile also includes metabolic risk markers such as insulin, glucose, Glycomark, leptin, adiponectin, and their ratio, offering a holistic view of factors influencing cardiovascular health.

DNA Methylation Pathway Profile

Uses buccal swab samples and real-time PCR technology to genotype various genes involved in methionine metabolism, transmethylation, and transsulfuration. This test provides insights into genetic variations within pathways crucial for processes like DNA and protein synthesis, and the production of important molecules such as glutathione and taurine. The report lists gene variations, indicating whether a mutation is present (heterozygous or double mutation), and includes details like collection, receipt, and report dates. Developed by Kashi Clinical Laboratories, Inc., this test is not intended as the sole basis for clinical diagnosis or patient management.

Cycle Mapping

Cycle Mapping provides a detailed look at a woman's hormonal fluctuations throughout her menstrual cycle. This testing tracks estrogen (E1 and E2) and progesterone (Pg) patterns across the cycle days, allowing for the identification of normal ranges and potential irregularities. It helps determine if ovulation is occurring and assesses the balance between estrogen and progesterone, offering insights into conditions like luteal phase defects or anovulation. The results, presented in easy-to-understand graphs and tables, help patients and healthcare providers understand hormonal health and guide personalized treatment strategies.

Small Intestinal Bacterial Overgrowth (SIBO)

A condition characterized by an increase in the number and/or the presence of atypical microbiota in the small intestine. Genova Diagnostics offers a SIBO breath test that measures hydrogen (H2) and methane (CH4) gases produced by intestinal microbiota following lactulose ingestion in a fasting state. This test helps evaluate the presence of SIBO by looking for a rise in hydrogen over baseline and/or a peak methane level. Understanding SIBO can be key to addressing various gastrointestinal concerns.

Urine Analysis

Primarily used to diagnose toxic element status, monitor detoxification therapies, and identify renal wasting conditions. While not a direct measure of nutritional status for essential elements, it can reflect recent exposure to toxic metals. Results are often corrected for creatinine levels to account for variations in urine dilution. Provocation tests with chelating agents can increase the urinary excretion of metals, but reference intervals for provoked samples have not been established.

DNA Core®

DNACore is useful for any patient where understanding the genetic foundations of their health challenges will enable a more personalised intervention. The test provides specific, tailor-made recommendations for the core components of any health strategy: weight management, exercise strategies, targeted diet and lifestyle interventions, and appropriate nutraceuticals required to support and optimise your everyday functioning. Implementing these core components allows for improved longevity and decreased risk of chronic disease.

DNA Gut

DNA Gut tests and reports on evidence-based, clinically useful, human genetic variants that predispose individuals to alterations in gut homeostasis. These alterations are known to have negative consequences for human health. The report offers personalised diet, lifestyle and nutraceutical interventions to support relevant pathways and help you achieve and maintain a healthy and resilient gastrointestinal tract.

DNA Health®

DNA Health® tests for genetic variations that are known to have a significant effect on health and susceptibility to chronic diseases. DNA Health reports on key biological pathways that govern overall health, and helps understand how genetic weaknesses in these pathways may increase predisposition to chronic diseases of lifestyle.

DNA Diet®

DNA Diet® is a genetic test designed to guide the personalisation of diet and lifestyle recommendations in order to manage weight. It provides insight into which diet type (low carbohydrate, low fat, or Mediterranean diet) would be most suitable for you according to your unique genetic makeup.

DNA Sport

DNA Sport is a genetic test that provides insight into various biological areas impacting training responsiveness and sports performance. The results of the DNA Sport test can be used to optimize performance by personalising your training program to enhance any genetic advantages and identify any weaknesses that need to be supported through training and nutrition strategies.

DNA Mind

DNA Mind reports on variants in 30 genes involved in key biological pathways, from serotonin and dopamine to inflammation and methylation, that have been shown to have significant associations with mental health, and provides personalised diet, lifestyle and nutraceutical recommendations as well as valuable ‘diagnostic insights’.

DNA Hormones

DNA Hormones is a comprehensive nutrigenetic test analysing and reporting on metabolism and detoxification of sex hormones. The DNA Hormones test analyses and reports on gene variants that have been shown to have an impact on sex steroid metabolism and biotransformation, affecting male and female health. DNA Hormones is an upgrade of, and will replace, the DNA Oestrogen test. The report offers personalised diet, lifestyle and hormone interventions to support relevant pathways and help you achieve and maintain optimal hormonal health and resilience and extended healthspan.

GrowBaby

GrowBaby is valuable for newly pregnant mums and mums to be. It can help optimise the chances of pregnancy as well as ensure a healthy pregnancy journey from pre-conception through to birth. Growbaby is a comprehensive test for mom-to-be which pairs with a wide array of other functional tests. These include organic acids, fatty acids, vitamin D, GI Map & other stool testing, methylation panel, DUTCH, cardiometabolic profile, environmental toxin exposure and essential elements.

DNA Smile

Oral health has a great impact on overall health and there is a growing evidence that supports the link between risk for periodontal disease and the development of other chronic diseases including cardiovascular disease, diabetes, certain cancers, and cognitive decline. DNA Smile is a genetic test designed to give insights into the state of oral health and predisposition for developing periodontal disease, tooth caries and other systemic diseases.

DNA Resilience

DNA Resilience is a genetic test targeted at individuals who want to lead more effectively (in business, sport, and life), cope better under stressful and demanding conditions, enhance their mental, emotional, and physical health, and live up to their fullest potential.